Climate Change, warming and/or ice age. gradual death of the human race.
Mega Volcano, we die because of lack of sunlight.
huge earthquake that causes major plate tectonics.
some other kind of natural disaster event?
Human intervention, nuclear war, machines take over etc.
Another race becomes dominant/sentient and kills us off.
Global Killer virus (Zombies)
God/biblical vengeance
No one thing will cause the extinction of the human race.
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( - Y - ) These ones are not real, just FYI.
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